You can take the guy out of the South Side, but you can’t take the South Side out of the guy … ‘cause Pope Leo XIV was spotted repping his White Sox at The Vatican!!

The pontiff ditched his zucchetto for a black ball cap during the general assembly in Rome this week … giving a wide grin as he showed support for his local baseball team.

Maybe word hasn’t made its way to Leo — the Sox stink right now with a 23-44 record … either that, or he’s still keeping the faith.

The White Sox have certainly embraced one of their supporters being top dog in the Catholic church — they even set up a mural in his honor inside the park with his own custom jersey and a pic of his appearance at the 2005 World Series.

Leo has received plenty of gifts after taking on the role — and has even gotten his own Bears jersey.